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About Us
Sagimet is a clinical-stage biopharmaceutical company developing novel fatty acid synthase (FASN) inhibitors that are designed to target dysfunctional metabolic pathways in diseases resulting from the overproduction of the fatty acid, palmitate. Sagimet’s lead drug candidate, denifanstat, is an oral, once-daily pill and selective FASN inhibitor in development for the treatment of NASH, for which there are no treatments currently approved in the United States or Europe. FASCINATE-2, a Phase 2b clinical trial of denifanstat in NASH with liver biopsy-based primary endpoints, was successfully completed with positive results. For additional information about Sagimet, please visit www.sagimet.com.
Position Summary:
The Associate Director, Drug Substance Manufacturing is responsible for supporting Sagimet’s drug substance activities, from early development through Phase 3 clinical supply to NDA registration activities and preparation for commercial manufacturing. This role is part of a team that leads all aspects of our Drug Substance activities at our contract manufacturing and contract development organizations (CMOs/CDMOs). In this role, you will provide synthetic and manufacturing technology expertise, drive process development/optimization, and lead technology transfers. Further, you will oversee drug substance clinical manufacturing, scale-up, registration batches, process validation, and commercial manufacturing preparedness.
Essential Responsibilities:
Education and Experience Requirements:
Compensation
The expected base salary range for this role is $155,000 - $195,000 Compensation will be based on a variety of factors, including experience, qualifications, and internal equity. Sagimet offers a competitive employment package that includes an annual bonus, equity, and a generous benefits package.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Notice to Recruiters/Staffing Agencies
Recruiters and staffing agencies should not contact Sagimet through this page. We require that all Recruitment Vendors (e.g., search firms, recruitment agencies and staffing companies) have a fully executed, formal written agreement on file with Sagimet prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited. Unsolicited vendor submissions do not constitute any actual or implied contract with Sagimet and Sagimet will not be responsible for any purported fees.
Full Time
$181k-227k (estimate)
06/24/2024
07/07/2024