1 Scientist, Oncolytics (Virology) Job in Philadelphia, PA
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Scientist, Oncolytics (Virology)
$128k-159k (estimate)
Full Time
1 Week Ago
Stealth Mode Biotechnology Company is Hiring a Scientist, Oncolytics (Virology) Near Philadelphia, PA
About Us:We are a startup biotechnology company dedicated to the development of novel cell therapies to cure cancers. The company was founded on pioneering work carried out in the laboratories of Dr. Carl June and Dr. Andy Minn (University of Pennsylvania), Dr. Kole Roybal (UCSF), and Dr. Christopher Garcia (Stanford University). We are using viral vectors, universal targets, and novel cytokine biology to enhance CAR T activity in solid tumors. Our therapeutic approach has potential to be used across multiple tumor types, enabling us to treat significant numbers of cancer patients.
Based in Philadelphia and San Francisco, we are backed with significant investment by prestigious investors including ARCH Ventures and the Parker Institute for Cancer Immunotherapy. At our company, you would become one of our early team members where you would help to define and hone our science, be a vital part of building our culture, and contribute to the company's future success. Here, you would collaborate with a top-notch team who care about patients and each other. We have an ownership mindset and are innovative, curious, driven, and resilient. We take time to build relationships because trust unlocks our ability to debate, share, forgive, and grow together - ultimately in service of our vision to create a universal cure for cancerous solid tumors and improve outcomes for patients.
The Role:We are seeking a highly motivated individual to join our team and take advantage of our state-of-the-art oncolytic virus/viral gene delivery and cell therapy systems capabilities to discover novel cancer immunotherapy approaches. This position will report to the Head of Oncolytics and focus on the characterization of various oncolytic virus candidates in combination with our core technologies.
Key Responsibilities:
Based in Philadelphia and San Francisco, we are backed with significant investment by prestigious investors including ARCH Ventures and the Parker Institute for Cancer Immunotherapy. At our company, you would become one of our early team members where you would help to define and hone our science, be a vital part of building our culture, and contribute to the company's future success. Here, you would collaborate with a top-notch team who care about patients and each other. We have an ownership mindset and are innovative, curious, driven, and resilient. We take time to build relationships because trust unlocks our ability to debate, share, forgive, and grow together - ultimately in service of our vision to create a universal cure for cancerous solid tumors and improve outcomes for patients.
The Role:We are seeking a highly motivated individual to join our team and take advantage of our state-of-the-art oncolytic virus/viral gene delivery and cell therapy systems capabilities to discover novel cancer immunotherapy approaches. This position will report to the Head of Oncolytics and focus on the characterization of various oncolytic virus candidates in combination with our core technologies.
Key Responsibilities:
- Isolate, expand, purify and characterize viruses emerging from genetically engineered viruses or those derived from directed evolution
- Evaluate novel replication competent virus candidates in high throughput in vitro assays utilizing cancer cell lines, organoids and primary cancer and normal tissue with respect to defining replication cycle time, and titer and VP:IVP ratio
- Support team members in the engineering of novel oncolytic viruses and the assessment of their potential for cancer treatment
- Communicate experimental findings in team meetings
- Analyze, document, and report laboratory data in accordance with company SOPs
- Present data and future experimental designs in meetings with scientific leadership
- Bachelor's or Master's degree in Virology, Cell Biology, Biochemistry or related field
- Prior experience in Discovery Research is imperative
- Experience in the generation, isolation/purification and evaluation of replication competent virus, viral vectors and/or virus engineering
- Hands-on experience in molecular biology, including plasmid purification, cloning and qPCR
- Ability to independently execute and interpret experimental assays
- Collaborative attitude, ability to work in a team and dedicated work ethic
- Strong organizational and planning skills and the desire to work in a flexible and fast-paced, entrepreneurial environment
- Strong verbal and written communication skills
- Prior experience with cell culture, culturing and isolation/purification of viruses
- Previous experience with analyses of purified virus and or viral vectors
- We offer a highly competitive compensation package with meaningful ownership
- Excellent coverage for medical, vision, dental
- 401(k) with generous match
- Life insurance
- Premium PTO policy
- Additional substantial benefits
Job Summary
JOB TYPE
Full Time
SALARY
$128k-159k (estimate)
POST DATE
06/22/2024
EXPIRATION DATE
07/16/2024
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