23 Bio Analytical Scientist Jobs in Seattle, WA
Synectics Inc. is Hiring a Bio Analytical Scientist Near Seattle, WA
- The Scientist will lead development of analytical methods to characterize process-related impurities and assess impurity clearance in autologous and allogenic cell therapies.
- Developing impactful methods, including QC methods for lot release testing and characterization methods that support process development and comparability assessments.
- These methods will be used to further our understanding of cell therapies, and support development of manufacturing processes, and/or QC release of the drug product.
- The successful candidate must have extensive hands-on experience in assay development and possess excellent communication skills in order to work on projects requiring close collaboration with other groups, such as discovery research, product sciences, process development, and QC.
- Will interface with external vendors (e.g., CMO's) for the successful management of any transferred analytical methods.
- Passionate about developing novel medicines, thrive in an intellectually challenging environment, and enjoy collaborating with a team of likeminded Scientists.
- Serve as a subject matter expert responsible for developing robust analytical methods and expanding product and process understanding.
- Independently develop and execute bioanalytical or molecular assays (e.g. chromatography, electrophoresis/CE assays)
- Identify issues, lead troubleshooting experiments, and determine solutions
- Train users on method execution, data analyses, and proper use of instrumentation
- Lead qualification and transfer of analytical methods to external stakeholders
- Routinely present work at team, technical team, and department meetings
- Maintain meticulous laboratory notebooks
- Analyzing, interpreting, and presenting data to internal and external stakeholders (Power Point Presentations)
- Author, review and approve technical documents, including methods, protocols, reports, and SOPs
- Deliver lifecycle-managed analytical methods for multiple programs with an understanding of ICH/FDA/EMEA best practices and current thinking.
- Facilitate smooth operation of the laboratory, including ordering, assisting in the cryopreservation of cellular material, sample management, etc.
- BS, MS or PhD in Molecular Biology, Analytical Biochemistry, Immunology, Microbiology, Cell Biology, or related field.
- PhD with 0-3 years; MS with 3 years; BS with 7 years of relevant industry experience.
- Proven experience with physicochemical analytical techniques such as chromatography, electrophoresis/CE, etc.
- Experience working with Waters UPLC system and Empower software
- Methods: SEC-U/HPLC, SEC-MALS, IEX, RP-LC, Affinity, CE: PA800 (SCIEX) CE-SDS, CZE, cIEF
- Experience with proteins characterization preferred
- Strong problem-solving ability to troubleshoot complex technical and scientific problems.
- Experience with writing technical and regulatory documents for interdepartmental use and external vendors (e.g., CMO's).
- Strong attention to detail.
- Outstanding written and oral communication skills.
- Work effectively in a collaborative team setting.
- Ability to work in a rapidly changing environment with frequent changes in priorities.
- Knowledge of immunology and T cell biology as applied to the cell therapy field
- Knowledge or experience with vector and gene editing analytics (AAV, CRISPR, etc.)
- Experience with molecular techniques (e.g., qPCR, RT-qPCR, and/or ddPCR).
- Experience with data analysis and interpretation using software (e.g., Softmax Pro, Gen5, Excel, Prism Graphpad).
- Familiarity with statistical analysis and design on experiments (DoE) using JMP software.
- Track record of successful transfer and management of analytical methods has context menu
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.
Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.
Synectics is an equal opportunity employer.
Job Summary
Contractor
Wholesale
$104k-130k (estimate)
06/20/2024
07/18/2024
synectics.net
LEBANON, OH
25 - 50
1993
HEIDI BALE
<$5M
Wholesale
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About Synectics Inc.
Environmental Synectics, Inc. (Synectics) is a HUBZone certified small business enterprise with more than 25 years of experience providing environmental services, information technology services and advisory & assistance services to federal government agencies as well as commercial and Fortune 500 companies. Since our founding in 1993, we have successfully executed work for the U.S. Air Force, Army and Navy at scores of installations nationwide. Synectics architected and implemented the environmental industrys most versatile cloud-based data management system with integrated Automated Data Rev...iew (ADR) capabilities. Our Environmental Data Management System (EDMS) requires only a secure internet connection to allow project teams around the globe access to datasets, report generation capabilities, and communication with colleagues. Synectics EDMS provides comprehensive functionality to all environmental projects and is backed by a team of professionals committed to leveraging innovative technologies to optimize processes, reduce costs and shorten schedules for the benefit of our clients.
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