In Vivo Pharmacology runs pre-clinical studies for external customers in areas of Oncology, Neurobiology, Autoimmune Diseases. Working under limited supervision, the In Vivo Technologist II is fully proficient with latitude for independent judgement; performs advanced biomethods, including complex tasks, and highly developed procedures. Additional responsibilities include understanding study timelines and communicating issues effectively. The level II technologist is expected to proactively seek out new opportunities that will enhance the team such as serving as a mentor, checking for quality gaps, organizing lab spaces for inspections and audits and understanding scientific content. Staff members may be required to work weekend shifts, holidays, and overtime. Working under limited supervision, the In Vivo Technologist II performs proficiently regular and advanced wet lab procedures, may assist in mouse injection and phenotyping, understands project timelines, is able to communicate complex scientific results efficiently with peers and supervisors. The level II technologist proactively seeks out new opportunities that will enhance the team such as checking for quality gaps, and organizing lab spaces for inspections and audits and This position maybe required to work weekend shifts, holidays, and overtime. Key Responsibilities & Essential Functions: • Execution of drug formulation protocols, and drug administration to mice • Wet lab molecular biology and biochemistry experiments such as gene expression/qPCR, protein analyses by Western Blot, blood cell/splenocyte isolation, FACS, immunoassays, • Computer-assisted image analyses and data management • Live animal phenotypic testing (eg. Electromyography, locomotor and behavioral testing) • Adhere to all SOPs, policies and regulatory procedures • Accurate data entry including lab IT systems and databases. Maintain appropriate documentation as required by protocols and SOPs. • Training to perform above procedures to proficiency levels and/or participate in the development of new procedures. • Lab Maintenance – Perform general lab sanitation, maintain consumables and reagents, and maintain equipment through calibration, validation and monitoring. • Other duties as assigned The wage range is $26.76 - $38.80 per hour. Pay will be determined based upon qualifications and experience. Qualifications: • BS degree with 1 year of applicable work experience or High School diploma with 3 or more years’ applicable work experience in a laboratory/animal care setting or all requirements for a Technologist II have been met. • Demonstrated ability in execution and development of research protocols. • Capable of performing a wide range of animal biomethods, and/or complex procedures. • Lab equipment operation experience. • Excellent communication and listening skills with proven ability to effectively communicate with others both verbally and in writing on scientific and technical topics,. • Proven excellent writing skills. • Excellent problem-solving skills and ability to work effectively in a team environment. • Ability to work independently with minimal oversight. Ability to make decisions that adhere to all SOPs, policies and regulatory procedures. • Able to work in in vitro and in vivo environments, especially with animal handling. • Advanced computer skills in Word, Excel and statistical analyses, ability to develop technical documents and presentations • Ability to work flexible shifts (evening/weekend/holiday) #CA-DS5 About JAX: The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org. EEO Statement: The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws. Bar Harbor: The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries. Ellsworth: The Charles E. Hewett Center in Ellsworth, Maine, is a state-of-the-art facility that serves researchers world wide. The facility represents the culmination of nine decades of unmatched experience and leadership in breeding and caring for laboratory mice. Ellsworth, Maine, is one of Maine’s fastest growing cities. With a growth rate of nearly 20%, Ellsworth is a bustling year-round community and acts as a hub for surrounding towns. It is located nearby Acadia National Park and hosts numerous special events, concerts and festivals each year. Residents have access to fabulous shopping, recreation, museums, galleries, and dining at a variety of independent restaurants. Farmington: JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup. JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories. In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports. Sacramento: The JAX® Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California. Sacramento is less than a two-hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County. Sacramento is the birthplace of the nation’s Farm to Fork movement, and offers excellent restaurants, gastro-pubs, wineries, theaters, and museums. Outdoor activities are plentiful: Boating, white water rafting, and riding the scenic bicycle trails are popular. Housing and other costs of living are more affordable in Sacramento and its surrounding suburbs than in most other neighboring areas in the North Bay, making Sacramento one of the hottest housing markets in the country year after year. Augusta: JAX’s Maine Cancer Genomics Initiative (MCGI) is located in Augusta, Maine, in the Harold Alfond Center for Cancer Care (HACCC), at Maine General Hospital. It began operations in 2016 with three overarching goals: to provide cancer genomic testing for Maine cancer patients; to develop and deliver physician education about clinical genomic cancer diagnostics; and to build a network in Maine of oncology practices conducting studies in genomic medicine.