Research Assistant II, Neurogenetics and Autism Research

Izumi lab is a translational genetic research laboratory located in the Pediatrics Department at UT Southwestern. The research targets of Izumi lab are rare pediatric genetic disorders/autism diagnoses such as CHOPS syndrome and CBX1-related syndrome, and we use patient-derived samples and mouse models of these diagnoses for molecular investigation. Using cutting-edge genomic technologies, we hope to understand the disease mechanism of genetic disorders with the ultimate goal of identifying therapeutic strategies ameliorating clinical symptoms of these diagnoses.

Laboratory Expectations

·Daily routine includes cell/tissue culture (mainly induced pluripotent stem cells), basic molecular biology experiments (PCR, DNA extraction, RNA extraction, immunoblotting, qPCR, droplet digital PCR, DNA/RNA fluorescent in situ hybridization (FISH), CRISPR-Cas9 genome editing, immunohistochemistry staining etc.).

·Experience wet-bench lab technician.

·Basic molecular biology experiment experience (more than 3 years) is necessary.

·Induced pluripotent stem cell (iPSC) culture/neuronal differentiation experience is preferred.

·Lab management experience including sample coordination and interactions with an institutional review board.

·Experience handing research animals (mouse) is required.

Experience and Education

·Master's degree with major coursework in field of assignment and one (1) year experience as Research Assistant I or equivalent. or

·Bachelor's degree with major coursework in field of assignment and two (2) years’ experience to include one (1) year as Research Assistant I or equivalent. or

·Completion of two (2) years of college or specialized training in histology, serology, medical technology, etc. and five (5) years’ experience to include one (1) year as Research Assistant I or equivalent. or

·High school graduation with courses in basic sciences and seven (7) years’ experience to include one (1) year as Research Assistant I or equivalent.

Job Duties

·Plans, coordinates, and supervises assigned research projects, which may be limited as segment of larger project, exercising responsibility for project performance and accountability for progress; and/or personally performs advanced scientific and medical research work, suggesting modifications to, or improvements in, design of research projects, presenting original ideas for follow-up studies, and recommending utilization of new or revised techniques and procedures to obtain desired results.

·Constructs, assembles, and operates experimental or other specially designed laboratory apparatus and equipment.

·Assembles and analyzes research data.

·Assists in preparation of research material for reports or publication.

·May supervise a group of Research Technicians and/or Research Assistants of lower grade, making work assignments, advising on work procedures and reviewing work in process and upon completion.

·Performs other duties as assigned.

To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community.As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.