The position calls for a motivated biological scientist to join the Molecular Pharmacology group within the WCNDD. The Pharmacology team is responsible for conducting high-throughput screening assay of small molecule modulators of GPCRs, ion channels, and kinases. This includes development of target protein cell lines and pharmacological assay to lead and support all molecular pharmacology activities. This position is a key contributor to support the Center’s goal of developing therapeutics, specifically for central nervous system disorders. Successful candidates will interface with members among all areas of the WCNDD, including those in molecular pharmacology, medicinal chemistry, drug metabolism and pharmacokinetics, and in vivo rodent pharmacology.

We are all different, yet we all use our unique contributions to serve patients. The Molecular Pharmacology Drug Discovery Scientist we seek is a person with these qualifications. 

• Oversee/facilitate the design, execution, analysis, and reporting of small molecule screening in in vitro pharmacological assay.
• Conduct high-throughput cell-based screening assays in support of characterizing GPCR, ion-channel, kinase targeted small molecule drugs. 
• Operate multi forms of liquid handling equipment, and automation units.
• Develop stable cell lines specific to new target proteins.
• Perform molecular biology experiments involving preparation and analysis of DNA/RNA and Protein.
• Train research associates in pharmacological assay, equipment operation/maintenance, and data analysis. 
• Write up pharmacological assay protocols.
• Analyze data to determine the efficacy and potency of the compounds using data analysis software. 
• Maintains accurate databases and experimental notebooks of results.