Reporting to: National Director, Field Medical Affairs
Do you have the passion and commitment to join a group whose mission is to develop treatments that have a clear and profound impact on patients suffering from rare diseases? Does it excite you to be a part of a patient-focused company developing potential new treatments that could dramatically improve the lives of patients with limited to no current treatment options? If yes, we encourage you to share with us your aspirations and career goals.
X4 is focused on restoring healthy immune system function by developing novel therapeutics to treat chronic neutropenic disorders, including WHIM syndrome, a rare primary immunodeficiency. We are advancing a novel, late-stage clinical candidate, mavorixafor, that we believe has the potential to become a new standard of care for patients with these disorders. We know that developing innovative, new medicines is challenging, and we invite new colleagues who share our values and commitment to join us in achieving our mission.
This opportunity will …

• Align with your values and grit, and passion for innovative science.
• Leverage your deep knowledge of medical science, education, and research to support our innovative science and allow you to have a major impact on our mission to support our patients.
• Offer a collegial environment with a team-based approach, where our mission drives our values, behaviors, and creativity.

Accountabilities And ResponsibilitiesThe Senior Medical Science Liaison (MSL) is a field-based (Southeast Region) clinical and scientific expert primarily responsible forthe dissemination of clinical and scientific information to support X4’s Rare Primary Immunodeficiencies (PID) and Chronic Neutropenia portfolio. They will be primarily responsible for communicating clinical and scientific information as it relates to the application of X4’s molecules across all therapeutic areas to Healthcare Practitioners (HCPs) and payers and professional societies. Other key aspects of this role include the gathering and communication of insights from key external stakeholders that will inform and guide strategic planning, supporting ongoing data generation activities and collaboration with internal X4 stakeholders.

• Build and execute a territory strategy and tactical plan in alignment with medical affairs plan.
• Develop and maintain effective professional relationships with key external stakeholders to build a network of Key Opinion Leaders for medical and scientific exchange and research initiatives.
• Provide in-depth drug and disease state medical and scientific information to HCPs.
• Have clinical and scientific discussions with potential investigators to ensure overall quality of study endpoints, including but not limited to understanding of clinical protocols, study feasibility, and enrollment. Convey KOL and site staff feedback and insight to internal and external teams.
• Conduct targeted conversations with the investigators and site staff regarding operational challenges, including but not limited to those related to patient recruitment and retention.
• Communicate field feedback and actionable insights to internal X4 stakeholders on a regular basis.
• Attend key medical congresses at the national level and regional society meetings supporting scientific and corporate goals.
• Keep up to date with product information, scientific evidence, and therapeutic landscape.
• Hold knowledge of industry trends, relevant healthcare systems, the regulatory and payor environment.
• Serve as a liaison to HCPs and professional organizations, and disease state advocacy groups. Support the efforts of patient support groups and educational foundations.
• Provide medical and scientific input into the planning and execution of advisory boards and MSL roundtables. Work with KOLs to review presentations and provide additional medical education where requested.
• Work in partnership with X4 field personnel to compliantly provide in depth disease state and product medical education.
• Generate Custom Medical Response Letters upon receipt of medical inquiries and respond to unsolicited Medical Information requests.
• Respond to unsolicited requests regarding interest in investigator sponsored studies (ISS) and support their submission through appropriate internal process.
• Partner closely with investigators and internal stakeholders to support site identification and clinical trial enrollment.
• Accountable for meeting corporate goals and objectives while keeping in compliance with applicable policies and regulations.
• Requires 60 – 70% travel.

Requirements: Proven Experience, Skills, and Education:

• PharmD, PhD, or MD preferred, but will consider NP/PA/MSN with clinical experience.
• Minimum 5 years of MSL experience.
• Rare Disease and/or Immunology and/or Hematology experience preferred, but not required.
• Creative problem-solver with strong business acumen and skills.
• Able to work independently with exceptional time management and organizational skills.
• Proven track record of success in establishing relationships with opinion leaders.
• Ability to understand and clearly communicate evidence-based scientific information.
• Ability to work collaboratively and cross-functionally, showing sound decision making and accountability.
• Experience in clinical research, patient recruitment, and investigator sponsored trials.
• Passionate about making a meaningful difference in patient care.
• This role is field-based and residency in the assigned territory (Southeast US – Florida, Georgia, Mississippi, Alabama, Tennessee, North Carolina, or South Carolina) is required.

We encourage you to learn more about X4 Pharmaceuticals. Click on the links below!
About UsPipelineX4 Pharmaceuticals is an Equal Opportunity, and Affirmative Action Employer committed to a culturally diverse workforce. All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law.
Please note that effective January 1, 2022, as a condition of employment at X4 Pharmaceuticals, all employees and new employees must have received their complete doses of the COVID-19 vaccine and one booster unless they have been granted an exemption by X4.