Associate Scientist (Manufacturing Sciences – Scale Up Lab)

Associate Scientist (Manufacturing Sciences – Scale Up Lab) Do you have a passion for science? Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the place for you! At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person. About AstraZeneca in Gaithersburg, MD: Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most powerful technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. Summary of the group: The Manufacturing Sciences Scale Up Lab (SUL) is responsible for production of cell culture and microbial materials for development, toxicology, and process scale-up studies in a non-GMP environment. This team works closely with process development scientists, process engineers, automation scientists, and the technical transfer group to demonstrate process scale up and technology capabilities. Main Duties & Responsibilities: Planning, executing, and troubleshooting 50L to 200L bioreactors and continuous downstream operations in an R&D setting for fed-batch and perfusion cell culture processes Planning, executing, and troubleshooting of a 30L single use fermenter for microbial processes Harvest operations including continuous flow centrifuges, depth filtration, and TFF Test, implement, and operate various process analytical technologies (PAT) Apply coding skills to increase efficiencies and improve automation Produce data and material for downstream development, toxicology, formulation, and stability studies Make detailed observations, analyze data, interpret results, and present data at group and department meetings Evaluate new technologies and implements new tools to improve process outcomes Education & Experience Requirements: Education: Bachelor’s or Master’s degree in Biology, Biochemistry, Bioprocess Engineering, Chemical Engineering, or related life sciences field. Experience: Bachelor's or Master's degree and 0 years of related industry experience Required Skills: Fundamental understanding of important quality attributes necessary for cell culture, fermentation, and purification Strong problem solving, experimental design, organizational, presentation, and documentation skills Ability to work in a team environment or independently Requires periodic weekend work Desired Skills: Knowledge of engineering principles including mass transfer and application to bioprocessing Experience culturing CHO and HEK cell lines; purification techniques of monoclonal antibodies Fermentation experience, E. coli preferred Experience working with pilot scale bioprocessing equipment (>50L) Programming experience (VB.net, python, etc.) Why AstraZeneca? At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, groundbreaking methods, and bringing unexpected teams together. Interested? Come and join our journey. So, what’s next? Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours. Where can I find out more? Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/ Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/ Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en Date Posted 23-Jun-2023 Closing Date 29-Jun-2023 AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law. AstraZeneca is an exciting global, innovation-driven biopharmaceutical company. We’re inspired by what science can do. Driven by the desire to meet unmet patient needs in our core therapeutic areas. Bold in our thinking. Proactive in pursuing discoveries beyond imagination. At sites across the world, we bring teams together in a spirit of collaboration to turn great ideas into life-changing medicines – strengthening our product portfolio and harnessing the potential of a pipeline across all stages of the drug development process. You’ll be part of a team that’s rolling back the frontiers of science to turn yesterday’s impossible into the normal of tomorrow. So, if you share our focus and passion, join us and make a difference to patients – and in return, we’ll help you develop way beyond what you thought possible.