What are the responsibilities and job description for the Molecular Biologist position at Integrated Resources, Inc ( IRI )?
Description:
Job Title: Scientist - DNA Platform (Contractor)
Job Summary: We are seeking an experienced molecular biology scientist to support mRNA vaccine research and development by focusing on DNA production, purification, and analytical technologies. Key skills include proficiency in molecular biology techniques such as DNA sequence design, PCR, molecular cloning, DNA purification, and DNA analytics (e.g., gel electrophoresis, quantification). Preferred skills include experience with isothermal cell-free DNA amplifications, AKTA chromatography, next-generation sequencing (NGS), and biostatistics.
Key Responsibilities:
1. Design and Produce DNA Materials for mRNA-Based Medicine R&D
• Computationally design DNA sequences for target antigens.
• Perform molecular cloning, bacterial culture, and plasmid DNA extraction.
• Conduct DNA purification at various scales.
• Carry out analytical experiments for quality control.
2. Innovate and Develop Processes to Improve DNA Production Technologies
• Optimize existing DNA production and purification processes.
• Innovate and develop processes to improve DNA production, including cell-based and cell-free approaches.
• Troubleshoot experimental challenges and discover solutions.
• Contribute to establishing DNA production protocols and guidelines.
3. Collaborate with Cross-Functional Teams
• Communicate with teams.
• Provide scientific input for project goals.
Required Qualifications:
• MS with 5 years or Ph.D. with 0-1 years of post-graduate experience in molecular biology, synthetic biology, or a related field.
• Minimum of 3 years of hands-on experience with molecular biology experiments, including DNA sequence design, PCR, cloning, purification, and analytics.
• Experience or knowledge with AKTA chromatography.
• Extensive experience with process optimization and assay development.
• Ability to work efficiently in a fast-paced environment.
• Strong problem-solving skills and attention to detail.
• Excellent record-keeping, collaboration, and communication skills.
• Ability to design and execute experiments independently.
Preferred Qualifications:
• Experience or knowledge with isothermal amplification techniques.
• Experience or knowledge with biostatistics, including the use of software (e.g., JMP, Python, Matlab).
Contract Duration: 1 year
Location: Waltham, MA
