Principal Scientist

Principal Scientist, Immune-Oncology

Canton (Greater Boston), MA

Full time

Job Description :

We seek a dynamic and collaborative Principal Scientist to spearhead our Immune-Oncology Drug Development efforts. The Principal Scientist will design, conduct, and analyze key mechanism-of-action studies, support lead optimization, and candidate development studies, and establish early signs of efficacy, through proof-of-concept studies using in vitro, ex vivo, and in vivo models. This pivotal role demands a hands-on scientist who thrives in a dynamic, fast-paced environment and is comfortable juggling multiple responsibilities within a resource-limited setting. In this role, you will take full ownership of Immune-Oncology projects, ensuring their success by leveraging your expertise, creativity, and resilience.

Key Responsibilities :

• Manages small-molecule and biological drug discovery programs, overseeing all phases of project execution with a focus on R&D outcomes.
• Spearheads the conceptualization and design of drug discovery programs to ensure the development of innovative Immune-Oncology therapies while taking full ownership of project outcomes.
• Design and perform mechanism of action studies.
• Work collaboratively with cross-disciplinary teams, including Medicinal Chemistry, Structural Biology, Protein Chemistry, and Biophysics.
• Identify and develop short-, mid-, and long-term R&D objectives alongside senior management.
• Prioritize and coordinate research activities and allocate resources between internal staff and external contract research organizations (CROs).
• Proactively communicate project strategy, anticipate potential issues, and recommend appropriate resource decisions.
• Stays informed of innovative methods and technologies and acts as a scientific thought leader within the company.

Qualifications

Job Type : Full-time, Work Permit, Equal Opportunity Employment. If you are interested send us your CV / Resume and a note to our recruiting team.