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Sr. Associate Scientist, Antibody Discovery

Prellis Biologics, Inc.
Berkeley, CA Full Time
POSTED ON 1/23/2025
AVAILABLE BEFORE 4/15/2025

Prellis Biologics uses proprietary technology to 3D print lymph node organoids, which we are using to generate in vitro human lymph node cocultures for generating antigen-specific B-cells.  We are seeking a Senior Associate Scientist, Antibody Discovery to join our Antibody Discovery team.  In this role you will be supporting high-throughput antibody discovery efforts, particularly using primary cell co-culture approaches.  The ideal candidate will have a strong background in molecular biology and cell culture work, with significant experience in supporting end-to-end antibody discovery campaigns.

Key Responsibilities :

  • Perform high-throughput cellular biology techniques, including but not limited to, cell culture, Flow Cytometry, Fluorescence-activated cell sorting (FACS), and ELISPOT.
  • Set up and maintain primary cell co-cultures using aseptic techniques. Develop, troubleshoot, and drive protocol optimization for enhanced efficiency and increased throughput.
  • Develop and optimize automation protocols for improved efficiency in molecular and cellular assays.
  • Collaborate with cross-functional teams in a fast-paced, matrixed environment. Maintain accurate records of experiments, analyze data independently, and present results in team meetin

Qualifications :

  • B.S in Molecular Biology, Immunology, Biotechnology, or related life science field with 4 years of experience, or M.S. with 2 years of relevant experience.
  • Strong proficiency in maintaining primary cell co-culture systems is required.
  • Proficiency in Flow Cytometry workflows and single cell sorting for sequencing.
  • Experience with FlowJo or comparable analysis software.
  • Have strong experience in single B-cell antibody discovery workflows with an end goal of identifying novel therapeutic candidates.
  • Have prior experience with operating SONY MA900 cell sorters and MACSQuant analyzers.
  • Thrive in collaborative environments and are open to a mentorship role within the team.
  • Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment.
  • Excellent communication skills and ability to document and present experimental results.
  • Salary : $130,000

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