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Sr. Associate Scientist

Prellis Biologics, Inc.
Berkeley, CA Full Time
POSTED ON 2/4/2025
AVAILABLE BEFORE 4/29/2025

We are seeking a Senior Associate Scientist, Antibody Discovery to join our Antibody Discovery team.  In this role you will be supporting high-throughput antibody discovery efforts, particularly using primary cell co-culture approaches.  The ideal candidate will have a strong background in molecular biology and cell culture work, with significant experience in supporting end-to-end antibody discovery campaigns.

Key Responsibilities :

  • Perform high-throughput cellular biology techniques, including but not limited to, cell culture, Flow Cytometry, Fluorescence-activated cell sorting (FACS), and ELISPOT.
  • Set up and maintain primary cell co-cultures using aseptic techniques.
  • Develop, troubleshoot, and drive protocol optimization for enhanced efficiency and increased throughput.
  • Develop and optimize automation protocols for improved efficiency in molecular and cellular assays
  • Collaborate with cross-functional teams in a fast-paced, matrixed environment.
  • Maintain accurate records of experiments, analyze data independently, and present results in team meetings. Qualifications :
  • B.S in Molecular Biology, Immunology, Biotechnology, or related life science field with 4 years of experience, or M.S. with 2 years of relevant experience.
  • Strong proficiency in maintaining primary cell co-culture systems is required.
  • Proficiency in Flow Cytometry workflows and single cell sorting for sequencing.
  • Experience with FlowJo or comparable analysis software.
  • Ideal candidates will have strong experience in single B-cell antibody discovery workflows with an end goal of identifying novel therapeutic candidates.
  • Ideal candidates will have prior experience with operating SONY MA900 cell sorters and MACSQuant analyzers.
  • Ideal candidates thrive in collaborative environments and are open to a mentorship role within the team.
  • Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment. Excellent communication skills and ability to document and present experimental results.

About Prellis Biologics

At Prellis we integrate human biology with machine learning. We aim to revolutionized drug discovery by harnessing the power of human immune system with tightly, integrated machine learning to develop next-generation antibody therapeutics with unparalleled speed, precision and safety. We are committed to empowering our pharmaceutical partners with access to the most promising fully human body candidate rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before.  Prellis Biologics is a pre-IPO biotech located in Berkeley CA with a team-oriented, inclusive, and family-friendly culture. Our growing pipeline target high unmet patient needs across therapeutics including metabolic, inflammation, and oncology disease. Prellis has raised funding from top investors, including Celesta, Khosla Ventures, SOSV, & Avidity Partners.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Prellis offers compelling benefits based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work / life balance, and career development opportunities that may include :

  • A competitive employee benefits package, including group medical, dental and vision coverage, life and disability insurance, flexible spending accounts and a 401(k) plan Stock-based long term incentives Bonus plan Holiday package including a 1 week winter shutdown Flexible work models, including remote and hybrid working arrangements, where possible
  • Application deadline

    Prellis does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

    Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

    We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

    Salary : $130,000

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    Job openings at Prellis Biologics, Inc.

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