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4D Molecular Therapeutics
Emeryville, CA | Full Time
$193k-245k (estimate)
9 Months Ago
Director, FP&A
$193k-245k (estimate)
Full Time | Scientific Services 9 Months Ago
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4D Molecular Therapeutics is Hiring a Remote Director, FP&A

At 4D Molecular Therapeutics, Inc. (“4DMT”), we boldly innovate to unlock the full potential of genetic medicines for countless patients. We are committed to breaking boundaries and daring to cure as we develop new and foundational products and product components through our growing technology platforms.

4DMT is a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines. We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products. We believe key features of our targeted and evolved vectors will help us create targeted product candidates with improved therapeutic profiles. These profiles will allow us to treat a broad range of large market diseases, unlike most current genetic medicines that generally focus on rare or small market diseases.

We have built a deep portfolio of AVV-based gene therapy product candidates, with five product candidates in clinical trials: 4D-150 for the treatment of wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME), 4D-710 for the treatment of cystic fibrosis lung disease, 4D-310 for the treatment of Fabry disease cardiomyopathy, 4D-125 for the treatment of X-linked retinitis pigmentosa (XLRP), and 4D-110 for the treatment of choroideremia. In addition, we have two product candidates in preclinical studies: 4D-175 for geographic atrophy (GA) and 4D-725 for alpha-1 antitrypsin deficiency.

To-date, we have demonstrated clinical proof-of-concept for three evolved vectors in three therapeutic areas and routes of administration with five products and patient populations. We believe this validates the power of our directed evolution platform for discovering superior vectors compared to wildtype viral vectors. We have built a robust and efficient product engine with 6 open Investigational New Drug Applications (INDs) in the U.S., 1 IND in Taiwan, and 1 Clinical Trial Approval (CTA) in Australia. We believe we are positioned to create, develop, manufacture and, if approved, effectively commercialize targeted genetic medicines that could transform the lives of patients suffering from debilitating diseases.

In addition to TVE, our technology includes a robust AAV manufacturing platform and onsite manufacturing facility that allows us to rapidly produce and test research grade material and scale up to GMP clinical material. This internal capability and close collaboration between our R&D and Manufacturing teams has greatly accelerated the pace of discovery at 4DMT.

Company Differentiators:

  • Fully integrated clinical-phase company with internal manufacturing
  • Demonstrated ability to move rapidly from idea to IND
  • Five candidate products in the clinic and two declared pre-clinical programs
  • Robust technology and IP foundation, including our TVE and manufacturing platforms
  • Initial product safety and efficacy data substantiates the value of our platforms
  • Opportunities to expand to other indications and modalities within genetic medicine

GENERAL SUMMARY:

The Director, FP&A will lead 4DMT’s Financial Planning and Analysis function, including annual budgeting, budget vs. actual reporting to various business teams and the Executive Team, cash runway model/long term planning, developing and maintaining business metrics, and also play a supporting role in Corporate Finance function, including execution of financing plan and supporting SEC reporting. This role will report to the Sr. Director, Corporate Finance, Investor Relations, and Corporate Communications, and will work collaboratively across the Company with functional heads, ClinOps Business Operations, and accounting to gather and analyze budget and actual data. The role will be hybrid with in-office work minimum of once per week.

RESPONSIBILITIES:

Build and Run FP&A Function: 70% of TIME

  • Cultivate and maintain partnerships with functional leaders / budget owners across the Company
  • Own and execute Annual Budget process with close coordination with Project Management
  • Own cash runway model
  • Report Budget vs. Actual to Leadership Team and functional leaders on a quarterly basis
  • Propose and implement FP&A reporting tool for BvA metrics across functional areas

Develop and Maintain Key Business Metrics: 10% of TIME

  • R&D Metrics:
  • Develop and maintain key operating metrics of the business (cost to develop programs by stage, etc.)
  • Operating Peers:
  • Work with Sr. Dir. Corp Fin to collect and document key comparable metrics vs. peers and regularly present findings / recommendations to leadership team

Ad Hoc Analyses: 10% of TIME

  • Various strategic initiatives expected to emerge throughout the year that require financial analysis (e.g., internal vs. enternalized business models)
  • Other duties as assigned, nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time

Support Corporate Finance efforts: 10% of TIME

  • Help support diligence / other needs for ATM, follow-on financings, other alternative financings
  • Help support Corporate Valuation model needs

QUALIFICATIONS:

Education:

  • Bachelor’s degree in Finance, Accounting, or related field, ideally some education experience such as certificate, minor, or concentration in biological sciences (e.g., biology, biochemistry, bioengineering)

Experience:

  • 10 years of finance-related experience within the Biotech or similar industry
  • 5 years of management experience within FP&A, specifically

Skills:

(non-technical and technical skills)

  • Advanced proficiency in MS Office Suite (Excel, PowerPoint, Outlook)
  • Detailed understanding and experience analyzing and forecasting all financial documents
  • Demonstrated industry knowledge of key performance metrics within the Biotech industry
  • Ability to understand and manage complex business scenarios and present financial and strategic impact
  • Experience operating standardized FP&A systems, implementation experience a plus
  • Leadership abilities in aligning on and executing on process to drive results

Physical Requirements of the Role:

  • Up to 5% travel

Base salary compensation range:

Minimum:

Maximum:

Bay Area Range:

$210,000

$249,000

Please note, the base salary compensation range and actual salary offered to the final candidate depends on various factors: candidate’s geographical location, relevant work experience, skills, and years of experience.

4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran, and any other category protected under applicable federal, state, provincial and local laws.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

Job Summary

JOB TYPE

Full Time

INDUSTRY

Scientific Services

SALARY

$193k-245k (estimate)

POST DATE

08/06/2023

EXPIRATION DATE

05/12/2024

WEBSITE

4dmoleculartherapeutics.com

HEADQUARTERS

EMERYVILLE, CA

SIZE

50 - 100

FOUNDED

2013

TYPE

Public

CEO

DAVID KIRN

REVENUE

$10M - $50M

INDUSTRY

Scientific Services

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About 4D Molecular Therapeutics

4DMT is a biotechnology company that researches, develops and commercializes gene therapeutics for the treatment of cancer.

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The following is the career advancement route for Director, FP&A positions, which can be used as a reference in future career path planning. As a Director, FP&A, it can be promoted into senior positions as a Top Financial Analysis Executive that are expected to handle more key tasks, people in this role will get a higher salary paid than an ordinary Director, FP&A. You can explore the career advancement for a Director, FP&A below and select your interested title to get hiring information.